Research

Anil Kumar

M. Sc.

Indian Institute of Technology, Roorkee

Ph. D.

Institute of Genomics and Integrative Biology (CSIR), New Delhi.

Email

anilk@nii.ac.in

 

Research Interest

Gut Microbiome

Summary of Research

The increasing evidences suggest that gut microbiota is going to influence the existing realms of healthcare and seems ready to offer promising approaches to improve human health and cure diseases in an effective way. The rapid developments in the study of gut microbiology are revealing the role of gut microbiota in digestion, the gut-brain axis, developing immune system and defending against pathogens. The perturbation in gut biodiversity has far reaching implications on human health and development. The research activitiesin my laboratory aim further investigation on the study of gut microbiome and how the result of the investigation may be helpful to devise strategies to promote human health and prevent diseases. We intend to identify more gut flora and their metabolites and understand the interactions of these metabolites within gut bacteria and with the host.

Awards/ Fellowships

CSIR Technology Award, 2012
Merck Millipore India Innovation Award, 2012
'Young Scientist Award’ from IUBMB, 2006.
‘Young Investigator Award’ from “HUPO 3rd Annual World Congress”, 2004.
FAOBMBTravel Fellowship.
Junior Research Fellowship (CSIR), 2003.
Merit Scholarship from Department of Biotechnology during M.Sc. at IIT Roorkee.

Inventorship in Patents (Granted)

US6896806 US7018510 US7022511 US7179633 US7267772
US7429478 US7736879 US7906008 US8080403 US7396671
EP1613739 EP1611282 EP1836133 EP1831682 EP1996520
GB1613739 GB1831682 GB1836133 GB1996520  IN221931
IN224060 IN231224 IN243806 IN244344 IN244801
FI120771 A2008/07816 ZA 2005/7593 CN352084 SE529680
CN 368495 FI1613739 SE1613739 DE1613739 CN200380110308.1
FR1996520 ZA 2007/5292 ZA2007/05230 ZA2007/05225  ZA2005/07609
FI1611282 AU2004326112 FR1611282 SE1611282 CNZL200480044738.2
DK1836133 AU2004326074 AU2004326080 DE1611282 AU2004326113
DK1831682 AU2007226332 BE1996520 DE1996520 CNZL200480044739.7
CH1996520 IT1996520 ES1996520 ZA2005/7592  

 

Selected Publications

  • Kulshreshtha NM, Kumar R, Begum Z, Shivaji S, Kumar A (2013) Exiguobacteriumalkaliphilum sp. nov. isolated from alkaline wastewater drained sludge of a beverage industry located in India Int J SystEvolMicrobiol, 63(Pt 12):4374-9
  • Majhi MC, Behera AK, Kulshrestha NM, Mahmooduzafar,  Kumar R, Kumar A (2012) Extreme: A unified web repository of extremophilic  microorganisms  PLoS ONE, 8(5): e63083. doi:10.1371/journal.pone.0063083
  • Gupta S, Saxena M, Saini N, Mahmooduzzafar, Kumar R, Kumar A (2012) An Effective Strategy for a Whole-Cell Biosensor Based on Putative Effector Interaction Site of the Regulatory DmpR Protein. PLoS ONE 7(8): e43527
  • Gahoi S, Mandal RS, Ivanisenko N, Shrivastava P, Jain S, Singh AK, Raghunandanan MV, Kanchan S, Taneja B, Mandal C, Ivanisenko VA, Kumar A, Kumar R, Open Source Drug Discovery Consortium, Ramachandran S (2012) Computational Screening for New Inhibitors of M. tuberculosis Mycolyltransferases Antigen 85 Group of Proteins as Potential Drug Targets. J Biomol Struct Dynam DOI:10.1080/07391102.2012.691343
  • Saini R, Kapoor R, Kumar R, Siddiqui TO and Kumar A (2011) CO2 utilizing microbes-A comprehensive review. Biotechnol Adv29(6):949-60.
  • Suresh PS, Kumar R and Kumar A (2011) Three dimensional model for N-terminal A domain of DmpR (2-dimethylphenol) protein based on secondary structure prediction and fold recognition. In Silico Biol 10(5):223-33
  • Rani A, Jain S, Dureja P, Kumar R and  Kumar A (2011) Synthesis of some 3-(5-chloro-1,3-diaryl-1H-pyrazol-4-yl)-1-arylprop-2-en-1-ones and 1,5-bis(5-chloro-1,3-diaryl-1H-pyrazol-4-yl)pent-1,4-diene-3-ones and their antimicrobial activity. Indian J Chem B Org 50B:1534-1531
  • Joshi S, Bisht GS, Rawat DS, Kumar A, Kumar R, Maiti S and Pasha S (2010) Interaction studies of novel cell selective antimicrobial peptides with model membranes and E. coli ATCC 11775. BiochimBiophys Acta 1798(10):1864-75
  • Saini R, Majhi MC, Kapoor R, Kumar A and Kumar R (2009) CSD: A database of CO2 utilizing strains. Environ Model Software 24(9):1133-1134
  • Suresh PS, Kumar A, Kumar R and Singh VP (2008) An Insilco approach to bioremediation: Laccase as a case study. J Mol Graph Model 26(5):845-849
  • Bisht GS, Rawat DS, Kumar A, Kumar R and Pasha S (2007) Antimicrobial activity of rationally designed amino terminal modified peptides. Bioorg Med Chem Lett 17(15):4343-4346
  • Manikandan S, Balaji S, Kumar A and Kumar R (2007) Comparative sequence analysis of acid sensitive and resistance proteins in Escherichia coli. Bioinformation 2(4):145-152

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