A Program for Detection
and Analysis of Polyketide Synthase Domains
Rajesh S. Gokhale and Debasisa Mohanty
SEARCHPKS is a software
for detection and analysis of Polyketide
This program facilitates easy identification of various PKS
domains and modules from a given polypeptide sequence. In addition it predicts the specificity of
the potential acyl transferase
domains for various
starter and extender precursor units. SEARCHPKS
is a user-friendly tool for correlating polyketide
chemical structures with the organization of domains
and modules in the corresponding modular polyketide synthases. This program also allows the user to extensively analyze and assess the sequence homology
of various polyketide synthase domains providing guidelines for carrying
out domain and module
The computational approach used in SEARCHPKS is based on a comprehensive analysis of various
characterized clusters of modular
polyketide synthases, compiled in PKSDB.
THE PROGRAM HERE
to view how the program has been integrated with PKSDB, the database of
characterized modular polyketide synthases.
to navigate the database of
characterized modular polyketide synthases (PKSDB).
Comments and suggestions to : Debasisa