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Publications 2022

Publications 2022

  1. Aggarwal S, Trehanpati N, Nagarajan P, Ramakrishna G. (2022) The Clock-NAD + -Sirtuin connection in nonalcoholic fatty liver disease. J Cell Physiol. 237:3164-3180.
  2. Ahuja R, Shelly A, Meena J, Panda AK. (2022) Microparticles entrapping pneumococcal protein SP0845 show improved immunogenicity and temperature stability. Int J Biol Macromol. 203:661-670.
  3. Ansari A, Sachan S, Jit BP, Sharma A, Coshic P, Sette A, Weiskopf D, Gupta N. (2022) An efficient immunoassay for the B cell help function of SARS-CoV-2-specific memory CD4+T cells. Cell Rep Methods. 2:100224.
  4. Bhatia I, Yadav S, Biswal BK. (2022) Identification, structure determination and analysis of Mycobacterium smegmatis acyl-carrier protein synthase (AcpS) crystallized serendipitously. Acta Crystallogr F Struct Biol Commun. 78:252-264.
  5. Chakrabarti A, Narayana C, Joshi N, Garg S, Garg LC, Ranganathan A, Sagar R, Pati S, Singh S. (2022) Metalloprotease Gp63-Targeting Novel Glycoside Exhibits Potential Antileishmanial Activity. Front Cell Infect Microbiol. 12:803048.
  6. Chakrabarti M, Garg S, Munjal A, Karan S, Pati S, Garg LC, Singh S. (2022) A Fast-Track Phenotypic Characterization of Plasmodium falciparum Vaccine Antigens through Lyse-Reseal Erythrocytes Mediated Delivery (LyRED) of RNA Interference for Targeted Translational Repression. Methods Mol Biol. 2410:539-553.
  7. Chauhan KS, Das A, Jaiswal H, Saha I, Kaushik M, Patel VK, Tailor P. (2022) IRF8 and BATF3 interaction enhances the cDC1 specific Pfkfb3 gene expression. Cell Immunol. 371:104468.
  8. Chowdhury S, Kar A, Bhowmik D, Gautam A, Basak D, Sarkar I, Ghosh P, Sarkar D, Deka A, Chakraborty P, Mukhopadhyay A, Mehrotra S, Basak S, Paul S, Chatterjee S. (2022) Intracellular Acetyl CoA Potentiates the Therapeutic Efficacy of Antitumor CD8+ T Cells. Cancer Res. 82:2640-2655.
  9. Dalal N, Lakshmi G.B.V.S, Singh A.k, Singh R, Kumar A (2022) MIP-based sensor for the detection of gut microbiota-derived indoxyl sulphate using PANI-graphene-NiS 2. Materials Today Chemistry. doi.org/10.1016/j.mtchem.2022.101157.
  10. Das S, Saha T, Yadav S, Shaha C. (2022) A Novel Role of Secretory Cytosolic Tryparedoxin Peroxidase in Delaying Apoptosis of Leishmania-Infected Macrophages. Mol Cell Biol. 42:e0008122.
  11. Dev G, Chawla AS, Gupta S, Bal V, George A, Rath S, Arimbasseri GA. (2022) Differential Regulation of Two Arms of mTORC1 Pathway Fine-Tunes Global Protein Synthesis in Resting B Lymphocytes. Int J Mol Sci. 23:16017.
  12. Dhembla C, Yadav U, Kundu S, Sundd M. (2022) Lipoate protein ligase B primarily recognizes the C8-phosphopantetheine arm of its donor substrate and weakly binds the acyl carrier protein. J Biol Chem. 298:102203.
  13. Dutta D, Santhanam SK, Parween F, Ismaeel S, Qadri A. (2022) Membrane prohibitin forms a dynamic complex with p56lck to regulate T cell receptor signaling. Immunol Lett. 241:49-54.
  14. Gupta A, Sharma D, Meena J, Pandya S, Sachan M, Kuma S, Singh K, Mitra K, Sharma S, Panda AK, Gupta P, Gupta UD, Misra A. (2022) Correction to: Preparation and Preclinical Evaluation of Inhalable Particles Containing Rapamycin and Anti-Tuberculosis Agents for Induction of Autophagy. Pharm Res. 39:1027-1028. Erratum for: Pharm Res. 2016 Aug;33(8):1899-912. PMID: 35438447.
  15. Gupta A, Vats A, Ghosal A, Mandal K, Sarkar R, Bhattacharya I, Das S, Pal R, Majumdar SS. (2022) Follicle-stimulating hormone-mediated decline in miR-92a-3p expression in pubertal mice Sertoli cells is crucial for germ cell differentiation and fertility. Cell Mol Life Sci. 79:136.
  16. Gupta I, Shankrit S, Narta K, Ghazi M, Grover R, Pandey R, Kar HK, Menon SM, Gupta A, Yenamandra VK, Singh A, Mukerji M, Mukhopadhyay A, Rani R, Gokhale RS, Dash D, Natarajan VT. (2022) Whole-Exome Sequencing of Vitiligo Lesions Indicates Lower Burden of Somatic Variations: Implications in Risk for Nonmelanoma Skin Cancers. J Invest Dermatol. 17:S0022-202X(22)02884-6.
  17. Gupta P, Mohanty D. (2022) Allosteric regulation of the inactive to active state conformational transition in CDPK1 protein of Plasmodium falciparum. Int J Biol Macromol. 215:489-500.
  18. Gupta P, Venkadesan S, Mohanty D. (2022) Pf-Phospho: a machine learning-based phosphorylation sites prediction tool for Plasmodium proteins. Brief Bioinform. 23:bbac249.
  19. Gupta S, Arora A, Saini V, Mehta D, Khan MZ, Mishra DK, Yavvari PS, Singh A, Gupta SK, Srivastava A, Kumar Y, Verma V, Nandicoori VK, Bajaj A. (2022) Hydrophobicity of Cholic Acid-Derived Amphiphiles Dictates the Antimicrobial Specificity. ACS Biomater Sci Eng. 8:4996-5007.
  20. Gupta S, Mishra DK, Khan MZ, Saini V, Mehta D, Kumar S, Yadav A, Mitra M, Rani P, Singh M, Nandi CK, Das P, Ahuja V, Nandicoori VK, Bajaj A. (2022) Development of a Highly Specific, Selective, and Sensitive Fluorescent Probe for Detection of Mycobacteria in Human Tissues. Adv Healthc Mater. 11:e2102640.
  21. Gupta SK, Toor S, Minhas V, Chaudhary P, Raman M, Anoop S, Panda AK. (2022) Contraceptive efficacy of recombinant porcine zona proteins and fusion protein encompassing canine ZP3 fragment and GnRH in female beagle dogs. Am J Reprod Immunol. 87:e13536.
  22. Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Poonam, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah P. (2022) The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+Homeostasis by Targeting a Unique Ion Channel. Pharmaceutics. 14:1371.
  23. Hakiem OR, Batra JK. (2022) Role of HrcA in stress management in Mycobacterium tuberculosis. J Appl Microbiol. 132:3315-3326.
  24. Hussain M, Saifi S, Mohammed A, Sengupta S. (2022) Protocol to detect in vitro and in cell ubiquitylation of mitochondrial DNA polymerase gamma by mitochondrial E3 ligase MITOL. STAR Protoc. 3:101710.
  25. Juyal G, Pandey A, Garcia SL, Negi S, Gupta R, Kumar U, Bhat B, Juyal RC, Thelma BK. (2022) Stratification of rheumatoid arthritis cohort using Ayurveda based deep phenotyping approach identifies novel genes in a GWAS. J Ayurveda Integr Med. 13:100578.
  26. Khandelwal M, Manglani K, Upadhyay P, Azad M, Gupta S. (2022) AdipoRon induces AMPK activation and ameliorates Alzheimer's like pathologies and associated cognitive impairment in APP/PS1 mice. Neurobiol Dis. 174:105876.
  27. Kumar S, Khan MZ, Khandelwal N, Chongtham C, Singha B, Dabla A, Behera D, Singh A, Gopal B, Arimbasseri GA, Kamat SS, Nandicoori VK. (2022) Mycobacterium tuberculosis Transcription Factor EmbR Regulates the Expression of Key Virulence Factors That Aid in Ex Vivo and In Vivo Survival. mBio. 13:e0383621.
  28. Kumar S, Perumal N, Yadav PK, Pandey RP, Chang CM, Raj VS. (2022) Amoxicillin impact on pathophysiology induced by short term high salt diet in mice. Sci Rep. 12:19351.
  29. Kumari G, Jain R, Kumar Sah R, Kalia I, Vashistha M, Singh P, Prasad Singh A, Samby K, Burrows J, Singh S. (2022) Multistage and transmission-blocking tubulin targeting potent antimalarial discovered from the open access MMV pathogen box. Biochem Pharmacol. 203:115154.
  30. Kumari V, Prasad KM, Kalia I, Sindhu G, Dixit R, Rawat DS, Singh OP, Singh AP, Pandey KC. (2022) Dissecting The role of Plasmodium metacaspase-2 in malaria gametogenesis and sporogony. Emerg Microbes Infect. 11:938-955.
  31. Lata S, Sood V, Banerjea AC. (2022) Human Immunodeficiency Virus Type 1 Vif Up-Regulates the Expression of Tat via AKT Signaling Pathway: Role of Ubiquitin Specific Protease 17. Front Microbiol. 13:828430.
  32. Meena J, Singhvi P, Srichandan S, Dandotiya J, Verma J, Singh M, Ahuja R, Panwar N, Wani TQ, Khatri R, Siddiqui G, Gupta A, Samal S, Panda AK. (2022) RBD decorated PLA nanoparticle admixture with aluminum hydroxide elicit robust and long lasting immune response against SARS-CoV-2. Eur J Pharm Biopharm. 176:43-53.
  33. Meena VK, Kumar V, Karalia S, Dangi RS, Sundd M. (2022) Structural and mechanistic insights into modulation of α-Synuclein fibril formation by aloin and emodin. Biochim Biophys Acta Gen Subj. 1866:130151.
  34. Mehdiratta K, Nain S, Sharma M, Singh S, Srivastava S, Dhamale BD, Mohanty D, Kamat SS, Natarajan VT, Sharma R, Gokhale RS. (2022) Respiratory Quinone Switches from Menaquinone to Polyketide Quinone during the Development Cycle in Streptomyces sp. Strain MNU77. Microbiol Spectr. 12:e0259722.
  35. Mehdiratta K, Singh S, Sharma S, Bhosale RS, Choudhury R, Masal DP, Manocha A, Dhamale BD, Khan N, Asokachandran V, Sharma P, Ikeh M, Brown AC, Parish T, Ojha AK, Michael JS, Faruq M, Medigeshi GR, Mohanty D, Reddy DS, Natarajan VT, Kamat SS, Gokhale RS. (2022) Kupyaphores are zinc homeostatic metallophores required for colonization of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 119:e2110293119.
  36. Mikaeloff F, Svensson Akusjärvi S, Ikomey GM, Krishnan S, Sperk M, Gupta S, Magdaleno GDV, Escós A, Lyonga E, Okomo MC, Tagne CT, Babu H, Lorson CL, Végvári Á, Banerjea AC, Kele J, Hanna LE, Singh K, de Magalhães JP, Benfeitas R, Neogi U. (2022) Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection. Commun Biol. 5:27.
  37. Mishra A, Ganguli N, Majumdar SS, Modi D. (2022) Loss of HOXA10 causes endometrial hyperplasia progressing to endometrial cancer. J Mol Endocrinol. 69:431-444.
  38. Mishra R, Kumawat KL, Basu A, Banerjea AC. (2022) Japanese Encephalitis Virus infection increases USP42 to stabilize TRIM21 and OAS1 for neuroinflammatory and anti-viral response in human microglia. Virology. 573:131-140.
  39. Mishra UK, Sanghvi YS, Abhiraj R, Sampathkumar SG, Ramesh NG. (2022) An expeditious synthesis of novel DNA nucleobase mimics of (+) -anisomycin. Carbohydr Res. 520:108645.
  40. Mohan KV, Mishra A, Muniyasamy A, Sinha P, Sahu P, Kesarwani A, Jain K, Nagarajan P, Scaria V, Agarwal M, Akhter NS, Gupta C, Upadhyay P. (2022) Immunological consequences of compromised ocular immune privilege accelerate retinal degeneration in retinitis pigmentosa. Orphanet J Rare Dis. 17:378.
  41. Mudgal R, Bharadwaj C, Dubey A, Choudhary S, Nagarajan P, Aggarwal M, Ratra Y, Basak S, Tomar S. (2022) Selective Estrogen Receptor Modulators Limit Alphavirus Infection by Targeting the Viral Capping Enzyme nsP1. Antimicrob Agents Chemother. 66:e0194321.
  42. Nair T, Chakraborty R, Singh P, Rahman SS, Bhaskar AK, Sengupta S, Mukhopadhyay A. (2022) Adaptive capacity to dietary Vitamin B12 levels is maintained by a gene-diet interaction that ensures optimal life span. Aging Cell. 21:e13518.
  43. Naiyer A, Khan B, Islam A, Hassan MI, Sundd M, Ahmad F. (2022) Heme-iron ligand (M80-Fe) in cytochrome c is destabilizing: combined in vitro and in silico approaches to monitor changes in structure, stability and dynamics of the protein on mutation. J Biomol Struct Dyn. 40:4122-4139.
  44. Naz S, Dabral S, Kumar D, Nandicoori VK. (2022) Protocol for ex vivo competition and sequencing of mycobacterium isolated from infected guinea pigs. STAR Protoc. 3:101804.
  45. Neogi U, Elaldi N, Appelberg S, Ambikan A, Kennedy E, Dowall S, Bagci BK, Gupta S, Rodriguez JE, Svensson-Akusjärvi S, Monteil V, Vegvari A, Benfeitas R, Banerjea A, Weber F, Hewson R, Mirazimi A. (2022) Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target. Elife. 11:e76071.
  46. Pandey M, Tiwari S, Johri S, Biswal BK, Sharma C, Pandey AK. (2022) Investigating a putative transcriptional regulatory protein encoded by Rv1719 gene of Mycobacterium tuberculosis. Protein J. 41:424-433.
  47. Papanai GS, Sahoo KR, Reshma G B, Gupta S, Gupta BK. (2022) Role of processing parameters in CVD grown crystalline monolayer MoSe2. RSC Adv. 12:13428-13439.
  48. Parray HA, Narayanan N, Garg S, Rizvi ZA, Shrivastava T, Kushwaha S, Singh J, Murugavelu P, Anantharaj A, Mehdi F, Raj N, Singh S, Dandotiya J, Lukose A, Jamwal D, Kumar S, Chiranjivi AK, Dhyani S, Mishra N, Kumar S, Jakhar K, Sonar S, Panchal AK, Tripathy MR, Chowdhury SR, Ahmed S, Samal S, Mani S, Bhattacharyya S, Das S, Sinha S, Luthra K, Batra G, Sehgal D, Medigeshi GR, Sharma C, Awasthi A, Garg PK, Nair DT, Kumar R. (2022) A broadly neutralizing monoclonal antibody overcomes the mutational landscape of emerging SARS-CoV-2 variants of concern. PLoS Pathog. 18:e1010994.
  49. Priyanka P, Sharma M, Das S, Saxena S. (2022) E2F1-induced lncRNA, EMSLR regulates lncRNA. Sci Rep. 12:2548.
  50. Rai H, Gupta S, Kumar S, Yang J, Singh SK, Ran C, Modi G. (2022) Near-Infrared Fluorescent Probes as Imaging and Theranostic Modalities for Amyloid-Beta and Tau Aggregates in Alzheimer's Disease. J Med Chem. 65:8550-8595.
  51. Raja R, Wang C, Mishra R, Das A, Ali A, Banerjea AC. (2022) Host AKT-mediated phosphorylation of HIV-1 accessory protein Vif potentiates infectivity via enhanced degradation of the restriction factor APOBEC3G. J Biol Chem. 298:101805.
  52. Rana K, Pani T, Jha SK, Mehta D, Yadav P, Jain D, Pradhan MK, Mishra S, Kar R, G BR, Srivastava A, Dasgupta U, Patil VS, Bajaj A. (2022) Hydrogel-mediated topical delivery of steroids can effectively alleviate psoriasis via attenuating the autoimmune responses. Nanoscale. 14:3834-3848.
  53. Ratra Y, Kumar N, Saha MK, Bharadwaj C, Chongtham C, Bais SS, Medigeshi G, Arimbasseri GA, Basak S. (2022) A Vitamin D-RelB/NF-κB Pathway Limits Chandipura Virus Multiplication by Rewiring the Homeostatic State of Autoregulatory Type 1 IFN-IRF7 Signaling. J Immunol. 18:ji2101054.
  54. Rawat RS, Bansal P, Sharma P. (2022) A VPS15-like kinase regulates apicoplast biogenesis and autophagy by promoting PI3P generation in Toxoplasma gondii. PLoS Pathog. 18:e1010922.
  55. Sachdeva R, Pal R. (2022) A pregnancy hormone-cell death link promotes enhanced lupus-specific immunological effects. Front Immunol. 13:1051779.
  56. Sahu D, Bishwal SC, Malik MZ, Sahu S, Kaushik SR, Sharma S, Saini E, Arya R, Rastogi A, Sharma S, Sen S, Singh RKB, Liu CJ, Nanda RK, Panda AK. (2022) Troxerutin-Mediated Complement Pathway Inhibition is a Disease-Modifying Treatment for Inflammatory Arthritis. Front Cell Dev Biol. 10:845457.
  57. Salini S, Bhat SG, Naz S, Natesh R, Kumar RA, Nandicoori VK, Kurthkoti K. (2022) The Error-Prone Polymerase DnaE2 Mediates the Evolution of Antibiotic Resistance in Persister Mycobacterial Cells. Antimicrob Agents Chemother. 66:e0177321.
  58. Sarkar D, Vijayan R, Gourinath S, Sau AK. (2022) A unique aromatic cluster near the active site of H. pylori CPA is essential for catalytic function. Biophys J. 121:248-262.
  59. Sarkar M, Sharma H, Singh P, Ranu R, Sharma RD, Agrawal U, Pal R. (2022) Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors. iScience. 25:104527.
  60. Singh Rawat B, Venkataraman R, Budhwar R, Tailor P. (2022) Methionine and Choline-Deficient Diet Identifies an Essential Role for DNA Methylation in Plasmacytoid Dendritic Cell Biology. J Immunol. 208:881-897.
  61. Singh SK, Shree A, Verma S, Singh K, Kumar K, Srivastava V, Singh R, Saxena S, Singh AP, Pandey A, Verma PK. (2022) The nuclear effector ArPEC25 from the necrotrophic fungus Ascochyta rabiei targets the chickpea transcription factor CaβLIM1a and negatively modulates lignin biosynthesis, increasing hostsusceptibility. Plant Cell. doi: 10.1093/plcell/koac372.
  62. Singhvi P, Panda AK. (2022) Solubilization and Refolding of Inclusion Body Proteins. Methods Mol Biol. 2406:371-387.
  63. Srivastava A, Garg S, Karan S, Kaushik S, Ranganathan A, Pati S, Garg LC, Singh S. (2022) Plasmodium falciparum Antigen Expression in Leishmania Parasite: A Way Forward for Live Attenuated Vaccine Development. Methods Mol Biol. 2410:555-566.
  64. Srivastava G, Bajaj R, Kumar GS, Gaudreau-Lapierre A, Nicolas H, Chamousset D, Kreitler D, Peti W, Trinkle-Mulcahy L, Page R. (2022) The ribosomal RNA processing 1B:protein phosphatase 1 holoenzyme reveals non-canonical PP1 interaction motifs. Cell Rep. 41:111726.
  65. Sultan F, Basu R, Murthy D, Kochar M, Attri KS, Aggarwal A, Kumari P, Dnyane P, Tanwar J, Motiani RK, Singh A, Gadgil C, Bhavesh NS, Singh PK, Natarajan VT, Gokhale RS. (2022) Temporal analysis of melanogenesis identifies fatty acid metabolism as key skin pigment regulator. PLoS Biol. 20:e3001634.
  66. Thiruvengadam R, Awasthi A, Medigeshi G, Bhattacharya S, Mani S, Sivasubbu S, Shrivastava T, Samal S, Rathna Murugesan D, Koundinya Desiraju B, Kshetrapal P, Pandey R, Scaria V, Kumar Malik P, Taneja J, Binayke A, Vohra T, Zaheer A, Rathore D, Ahmad Khan N, Shaman H, Ahmed S, Kumar R, Deshpande S, Subramani C, Wadhwa N, Gupta N, Pandey AK, Bhattacharya J, Agrawal A, Vrati S, Bhatnagar S, Garg PK (2022) Department of Biotechnology India Consortium for COVID-19 research. Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: a test-negative, case-control study and a mechanistic study of post-vaccination immune responses. Lancet Infect Dis. 22:473-482.
  67. Upadhyay P. (2022) The profit driven system can only lead to inequality, poverty, hunger and TB. Int J Tuberc Lung Dis. 26:901.
  68. Verma D, Sajwan RK, Lakshmi GBVS, Kumar A, Solanki P (2022) A Molecularly Imprinted Polymer based on Novel Polyaniline–Zinc Sulfide Nanocomposite for Electrochemical Detection of Trimethylamine N-Oxide. Environ Sci Nano. https://doi.org/10.1039/D2EN00624C.
  69. Verma P, Arora A, Rana K, Mehta D, Kar R, Verma V, Srikanth CV, Patil VS, Bajaj A. (2022) Gemini lipid nanoparticle (GLNP)-mediated oral delivery of TNF-α siRNA mitigates gut inflammation via inhibiting the differentiation of CD4 + T cells. Nanoscale. 14:14717-14731.
  70. Vikkurthi R, Ansari A, Pai AR, Jha SN, Sachan S, Pandit S, Nikam B, Kalia A, Jit BP, Parray HA, Singh S, Kshetrapal P, Wadhwa N, Shrivastava T, Coshic P, Kumar S, Sharma P, Sharma N, Taneja J, Pandey AK, Sharma A, Thiruvengadam R, Grifoni A, Weiskopf D, Sette A, Bhatnagar S, Gupta N. (2022) Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern. Nat Microbiol. 7:974-985.
  71. Yadav M, Jalan M, Srivastava M. (2022) Enhancer Dependent Repositioning of TCRb Locus with Respect to the Chromosome Territory. J Mol Biol. 434:167509.